Prevention of Acoustic Trauma Induced Hearing Loss by N-acetylcysteine Administration in Rabbits

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prevention of acoustic trauma-induced hearing loss by n-acetylcysteine administration in rabbits

background acoustic trauma is an injury to the hearing mechanisms in the inner ear due to excessive noise. this injury is the most prevalent cause of sensorineural hearing loss in humans, especially from occupational exposure. previous studies have shown the essential role of free radical formation in the inner ear hearing loss caused by acoustic trauma. objectives this study was performed to d...

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Prevention of Acoustic Trauma-Induced Hearing Loss by N-acetylcysteine Administration in Rabbits

BACKGROUND Acoustic trauma is an injury to the hearing mechanisms in the inner ear due to excessive noise. This injury is the most prevalent cause of sensorineural hearing loss in humans, especially from occupational exposure. Previous studies have shown the essential role of free radical formation in the inner ear hearing loss caused by acoustic trauma. OBJECTIVES This study was performed to...

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The Effect of N-Acetylcysteine Administration to Prevent Anthracycline-Induced Cardiotoxicity in Breast Cancer Patients

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Protective effects of N-acetylcysteine on noise-induced hearing loss in guinea pigs.

Increasing evidence suggests the involvement of oxidative stress in noise-induced hearing loss. The present study analysed, in an animal experimental model, the time course of the pathogenic mechanisms of noise-induced cochlear damage and the efficacy of the antioxidant drug N-acetylcysteine in reducing noise ototoxicity. Animals were divided into two groups, exposed to noise one treated with N...

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ژورنال

عنوان ژورنال: Archives of Trauma Research

سال: 2013

ISSN: 2251-953X,2251-9599

DOI: 10.5812/atr.7839